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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHM1
All Species:
9.39
Human Site:
S460
Identified Species:
22.96
UniProt:
Q9Y4G2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4G2
NP_055613.1
1056
117443
S460
E
Q
P
L
E
S
A
S
D
H
P
I
A
S
Y
Chimpanzee
Pan troglodytes
XP_001140498
1061
118011
S465
E
Q
P
L
E
S
A
S
D
H
P
I
A
S
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548048
1056
117749
S459
E
P
P
T
E
S
P
S
E
R
S
A
A
P
F
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSI1
1074
118516
A461
E
P
A
L
K
S
A
A
G
L
C
T
S
P
V
Rat
Rattus norvegicus
Q5PQS0
1059
117490
S458
E
H
A
L
K
N
T
S
D
L
C
I
S
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507582
964
103304
F421
G
S
D
F
G
A
L
F
P
A
A
A
A
K
T
Chicken
Gallus gallus
NP_001026095
1005
111261
P429
P
D
G
A
G
E
G
P
T
S
G
L
L
S
A
Frog
Xenopus laevis
Q08AW4
748
85595
F206
T
N
I
L
K
K
G
F
L
E
T
R
I
T
P
Zebra Danio
Brachydanio rerio
NP_001082872
845
95085
Q303
V
C
E
A
D
E
L
Q
P
P
P
S
V
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395844
660
73853
V118
L
S
Q
L
T
T
E
V
G
Y
C
R
A
W
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
N.A.
85
N.A.
82.7
83.2
N.A.
35.3
60.1
24.3
37.9
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
100
99.1
N.A.
89.1
N.A.
87.3
88.3
N.A.
47.9
73.1
41.1
53.8
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
100
100
N.A.
40
N.A.
26.6
33.3
N.A.
6.6
6.6
6.6
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
53.3
N.A.
46.6
53.3
N.A.
13.3
13.3
20
20
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
20
0
10
30
10
0
10
10
20
50
0
10
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
30
0
0
0
0
% C
% Asp:
0
10
10
0
10
0
0
0
30
0
0
0
0
0
0
% D
% Glu:
50
0
10
0
30
20
10
0
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
20
0
0
0
0
0
0
10
% F
% Gly:
10
0
10
0
20
0
20
0
20
0
10
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
20
0
0
0
0
10
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
30
10
0
10
% I
% Lys:
0
0
0
0
30
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
10
0
0
60
0
0
20
0
10
20
0
10
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
20
30
0
0
0
10
10
20
10
30
0
0
30
10
% P
% Gln:
0
20
10
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
20
0
0
0
% R
% Ser:
0
20
0
0
0
40
0
40
0
10
10
10
20
30
0
% S
% Thr:
10
0
0
10
10
10
10
0
10
0
10
10
0
10
10
% T
% Val:
10
0
0
0
0
0
0
10
0
0
0
0
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _